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The critical oncohematological patient

Edited by Ana Ochagavía Calvo - Department of Intensive Care Medicine. Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat (Barcelona), Spain

Last update: November 2025

The survival rates of many neoplasms have improved greatly in recent years, as a result of which we are often faced with a chronic, non-terminal disease. This situation poses a difficulty for the intensivist, since there is little information on the evolution and outcome of oncohematological patients admitted to the Intensive Care Unit (ICU). In addition, it is important to avoid pooling all cancer patients into one group, and thus to favor individualized treatment. Such treatment should be based on the creation of multidisciplinary teams with other specialties, such as Oncology and Hematology, and on subsequent monitoring in the ward with alert systems.

The critical oncohematological patient represents a challenge, a search, and a learning process for the intensivist: which patients have to be admitted to our Units? What is their evolution in the ICU? What is the prognosis of these patients once they are discharged from the ICU? Do we have specific mortality predictive models? What are the different treatments applied to patients with solid and hematological malignancies?

In this special supplement, articles of all formats published in 2024 and 2025 in Medicina Intensiva focused on the critical oncohematological patient have been compiled. The topics covered include clinical aspects such as thromboembolic complications or therapy involving the immune checkpoint inhibitor (ICI) group of drugs. In addition, the supplement includes papers that address very relevant topics such as the analysis of short- and long-term mortality in patients with solid malignancies, mortality predictive models, and the analysis of the reasons for rejecting cancer patient admission to the ICU.

This special supplement aims to provide practical and up-to-date information on the critically ill oncohematological patient for all professionals working in the ICU.

También disponible: El paciente crítico oncohematológico

Factors associated with short- and long-term outcomes in lung cancer patients requiring unplanned invasive mechanical ventilation
Emeric Chatelain, Marie Simon, Romain Hernu, Laurent Argaud, Martin Cour
Med Intensiva. 2024;48:37-45
Highlights

  • More than one-third of patients with lung cancer were successfully weaned off unplanned invasive mechanical ventilation and discharged from ICU.

  • The characteristics of lung cancer were not independently associated with weaning success or ICU survival.

  • Less than 1 in 5 patients was still alive 1year after intensive care unit admission.

  • Metastatic status and lung resection were the only 2 factors associated with long-term outcomes.

  • Most survivors with planned cancer treatment were able to receive treatment after discharge from the ICU.

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Open Article
Reasons for refusal of admission to the ICU in oncological population and their association with 6-month mortality
Elena Cuenca Fito, Alejandro González Castro, Inés Gómez Acebo
Med Intensiva. 2024;48:616-20
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Open Article
Incidence of venous thromboembolic disease and risk of bleeding in critically ill patients with hematologic malignancies: A retrospective study
Federico C. Carini, Laveena Munshi, Igor Novitzky-Basso, Graham Dozois, Camila Heredia, Sotirios Damouras, Bruno L. Ferreyro, Sangeeta Mehta
Med Intensiva. 2024;48:e1-e9
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Open Article
Towards better mortality prediction in cancer patients in the ICU: a comparative analysis of prognostic scales: systematic literature review
Andrea Cabrera Losada, Maria Alejandra Correa Oviedo, Vanessa Carolina Herrera Villazón, Sebastián Gil-Tamayo, Carlos Federico Molina, Carola Gimenez-Esparza Vich, Víctor Hugo Nieto Estrada
Med Intensiva. 2024;48:e30-e40
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Open Article
Removal of giant bronchial clot with cryoadhesion probe
Mónica García Simón, Cristina Sanchís Piqueras, Georgia García Fernández
Med Intensiva. 2025;49:189
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Open Article
Is it time to measure disease-free survival in critical oncology population?
Elena Cuenca-Fito, Eric Mayor-Vázquez
Med Intensiva. 2025;49:
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Open Article
What should intensivists know about immune checkpoint inhibitors and their side effects?
Viktor Yordanov Zlatkov Aleksandrov, Fernando Martínez Sagasti, Juncal Pérez-Somarriba Moreno, Helena Huertas Mondéjar
Med Intensiva. 2025;49:
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Development and validation of predictive mortality models in critically ill oncological patients in the ICU: An urgent need
Elena Cuenca Fito, Inés Gómez-Acebo, Alejandro González Castro
Med Intensiva. 2025;49:
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Short- and long-term mortality in critically ill patients with solid cancer. The Vall d’Hebron Intensive Care Unit-Vall d’Hebron Institute of Oncology Cohort: a retrospective study
Cándido Díaz-Lagares, Alejandra García-Roche, Andrés Pacheco, Javier Ros, Erika P. Plata-Menchaca, Adaia Albasanz, David Pérez, Nadia Saoudi, ... Ricard Ferrer
Med Intensiva. 2025;49:
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