Farmacocinética y farmacodinamia de ceftarolinaPharmacokinetics and pharmacodynamics of ceftaroline
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Cited by (5)
Ceftaroline versus standard therapy for pneumococcal meningitis in critically ill patients
2022, Medicina IntensivaCeftaroline removal during plasmapheresis
2022, Enfermedades Infecciosas y Microbiologia ClinicaAnimal models in the pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents
2016, Bioorganic and Medicinal ChemistryCitation Excerpt :The impact of route of administration on drug PK can also vary according to animal species and different drugs, for example the t1/2 of rifampicin in rats following intravenous administration was 4.7 h, which is shorter than the t1/2 (9.3 h) following oral administration, but the same increase in half-life was not evident in mice.29 However, some drugs are not affected by the route of administration and animal species, for instance, the PK parameters of ceftaroline administered through the intramuscular route in diverse animal species were similar to those observed when the drug was administered intravenously.30 Finally, even the strain of animal can affect the PK.
Treatment and prevention of invasive pneumococcal disease
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