Comentarios a artículos de investigaciónLos cuidados con clorhexidina bucal en la prevención de la neumonía asociada a ventilación mecánica a debateEffects of chlorhexidine gluconate oral care on hospital mortality: a hospital-wide, observational cohort study
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Comentarios
La neumonía asociada a ventilación mecánica es un efecto adverso grave, en gran parte evitable, de los pacientes críticamente enfermos. Las principales estrategias preventivas incluyen el fomento de prácticas seguras, mejorando aspectos como el retraso en la extubación, minimizando las microaspiraciones subglóticas y orofaríigeas utilizando clorhexidina oral como antiséptico en diferentes concentraciones para modular la colonización orofaríngea1.
Este procedimiento ha sido ampliamente estudiado
Bibliografía (6)
- et al.
Prevention of ventilator-associated pneumonia with oral antiseptics: a systematic review and meta-analysis
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Prevention of Ventilator-Associated and Early Postoperative Pneumonia Through Tapered Endotracheal Tube Cuffs: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
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(2018 Feb) - et al.
Chlorhexidine: an unrecognised cause of anaphylaxis
Postgrad Med J
(2014)
Cited by (1)
Should oral chlorhexidine remain in ventilator-associated pneumonia prevention bundles?
2022, Medicina IntensivaCitation Excerpt :In order to decide whether the adverse effects of oral chlorhexidine outweigh its benefits and recommend this practice to all critically ill patients on mechanical ventilation, some aforementioned information can be taken into account. The perception that oral chlorhexidine prevents VAP can be biased, since this data is present only in meta-analyses of “open-label” studies and not in double-blind ones18,52 and is speculated that its widespread use may be related with bacterial and antimicrobial resistance acquisition.24,48 Besides that, oral care with chlorhexidine for VAP prevention was associated with increase in ventilator associated events50 and mortality.14–16,18,45