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Vol. 47. Issue 11.
Pages 680 (November 2023)
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Vol. 47. Issue 11.
Pages 680 (November 2023)
Images in Intensive Medicine
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Necrotizing tracheobronchial aspergillosis in an immunosuppressed patient
Aspergilosis traqueobronquial necrotizante en paciente inmunodeprimido
José Luis Serrano-Martíneza,
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Corresponding author.
, Alberto Caballero-Vázquezb, María Núñez-Talaveraa
a Servicio de Medicina Intensiva, Hospital Universitario Virgen de las Nieves, Granada, Spain
b Servicio de Neumología, Hospital Universitario Virgen de las Nieves, Granada, Spain
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A 44-year-old male with a history of HIV infection with AIDS and Burkitt B-cell lymphoma was admitted to the ICU due to respiratory failure with neutropenia (80 cells/µl). Fibrobronchoscopy revealed extensive whitish-black exophytic lesions (Fig. 1, red asterisk) strongly suggestive of hyphae (Fig. 2, blue asterisks) lining the entire trachea (Video 1), carina and main bronchi (Video 2). Combination antifungal therapy was started with amphotericin B and caspofungin. Bronchoalveolar lavage confirmed the diagnosis of infection due to Aspergillus fumigatus. The mycosis presented a poor course, with mucosal necrosis and progression towards tracheoesophageal fistula and tracheal rupture that resulted in the death of the patient.

Figure 1
Figure 2
Conflicts of interest

All the authors declare that they have no conflicts of interest and have complied with all the applicable ethical standards.


The present study has received no funding of any kind.

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Copyright © 2023. Elsevier España, S.L.U. and SEMICYUC
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