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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Introducci&#243;n</span><p id="par0005" class="elsevierStylePara elsevierViewall">El c&#225;ncer es una enfermedad de incidencia creciente y responsable del 25&#37; de la mortalidad global en la poblaci&#243;n de nuestro pa&#237;s<a class="elsevierStyleCrossRef" href="#bib0155"><span class="elsevierStyleSup">1</span></a>&#46; La mejora de los tratamientos activos y de cuidados de soporte colaboran en la disminuci&#243;n de la mortalidad asociada al c&#225;ncer&#46; De este modo&#44; los pacientes afectados por neoplasias constituyen hoy una poblaci&#243;n susceptible de ingreso en las unidades de cuidados intensivos&#44; bien sea como parte del tratamiento del c&#225;ncer&#44; bien como tratamiento de procesos m&#233;dicos o quir&#250;rgicos intercurrentes&#44; bien como herramienta clave en el manejo de la toxicidad de los tratamientos oncol&#243;gicos<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">2</span></a>&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Esta mejora en la supervivencia obliga a replantearse el papel de la medicina intensiva en este escenario&#46; Distintas asociaciones cient&#237;ficas est&#225;n interesadas en entender este rol&#44; por lo que se han iniciado contactos entre grupos cient&#237;ficos interesados en el tema<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">3</span></a>&#46; En nuestro pa&#237;s se firm&#243; un acuerdo de colaboraci&#243;n entre la Sociedad Espa&#241;ola de Medicina Intensiva&#44; Cr&#237;tica y Unidades Coronarias &#40;SEMICYUC&#41; y la Sociedad Espa&#241;ola de Oncolog&#237;a M&#233;dica &#40;SEOM&#41; por el que se plante&#243; la realizaci&#243;n de un registro que proporcione informaci&#243;n sobre la epidemiolog&#237;a y los factores relacionados con la mortalidad de los pacientes oncol&#243;gicos que precisan ingreso en UCI<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">4</span></a>&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">En los &#250;ltimos a&#241;os se ha estudiado la supervivencia en UCI de distintos grupos de pacientes oncol&#243;gicos muy seleccionados<a class="elsevierStyleCrossRefs" href="#bib0175"><span class="elsevierStyleSup">5&#8211;9</span></a> &#40;principalmente hematol&#243;gicos&#41; y se han hecho recomendaciones sobre las distintas estrategias terap&#233;uticas<a class="elsevierStyleCrossRefs" href="#bib0160"><span class="elsevierStyleSup">2&#44;10</span></a>&#46; Tambi&#233;n se ha estudiado la evoluci&#243;n de pacientes oncol&#243;gicos sometidos a determinados procedimientos terap&#233;uticos propios de la medicina intensiva&#44; como ventilaci&#243;n mec&#225;nica<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">11&#8211;12</span></a>&#44; oxigenoterapia de alto flujo<a class="elsevierStyleCrossRef" href="#bib0215"><span class="elsevierStyleSup">13</span></a>&#44; t&#233;cnicas de depuraci&#243;n extrarrenal<a class="elsevierStyleCrossRef" href="#bib0220"><span class="elsevierStyleSup">14</span></a> o incluso sometidos a oxigenaci&#243;n extracorp&#243;rea<a class="elsevierStyleCrossRef" href="#bib0225"><span class="elsevierStyleSup">15</span></a>&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Sin embargo&#44; existen pocos datos epidemiol&#243;gicos generales sobre el impacto del ingreso de pacientes oncol&#243;gicos en las UCI&#46; En estudios multic&#233;ntricos la proporci&#243;n de pacientes con neoplasia ingresados en UCI oscila entre el 13&#37; y 20&#37;<a class="elsevierStyleCrossRefs" href="#bib0230"><span class="elsevierStyleSup">16&#8211;21</span></a>&#46; No obstante&#44; esta poblaci&#243;n es enormemente heterog&#233;nea&#44; lo que pudiera tener impacto en la atenci&#243;n y cuidados que requieren&#46; Es evidente que la estrecha relaci&#243;n multiprofesional y multidisciplinar es el &#250;nico camino posible para mejorar el pron&#243;stico de los pacientes cr&#237;ticos con c&#225;ncer<a class="elsevierStyleCrossRefs" href="#bib0170"><span class="elsevierStyleSup">4&#44;22&#8211;26</span></a>&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">El objetivo de este estudio es conocer la epidemiolog&#237;a&#44; los motivos de ingreso&#44; los recursos terap&#233;uticos empleados y la mortalidad de los pacientes con neoplasias malignas seg&#250;n la causa que origine su ingreso en UCI&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">M&#233;todos y pacientes</span><p id="par0030" class="elsevierStylePara elsevierViewall">Se realiza un estudio observacional tomando como base el registro ENVIN &#40;que denominamos &#171;base ENVIN&#187;&#41;&#46; Se incluyeron todos los pacientes ingresados entre el 1 de abril y el 30 de junio del a&#241;o 2018&#46; Se llev&#243; a cabo una ampliaci&#243;n de datos de pacientes oncol&#243;gicos asociando una nueva base de datos denominada &#171;base ONCOENVIN&#187;&#46; Tres variables comunes &#40;edad&#44; fecha de ingreso y sexo&#41; sirvieron para generar un identificador com&#250;n que permiti&#243; ligar los datos de una base y otra&#46;</p><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Selecci&#243;n de pacientes base ENVIN</span><p id="par0035" class="elsevierStylePara elsevierViewall">El registro ENVIN es un registro observacional&#44; de prevalencia de periodo y multic&#233;ntrico &#40;nacional&#41; de participaci&#243;n voluntaria&#46; El registro fue desarrollado en 1994 por el Grupo de Estudio de Enfermedades Infecciosas y Sepsis de la SEMICYUC&#46; Su objetivo es registrar la frecuencia y etiolog&#237;a de las infecciones asociadas a dispositivos empleados en la UCI&#46; Adicionalmente se registra el consumo de todos los antimicrobianos empleados durante el periodo de estudio&#44; as&#237; como la prevalencia de pat&#243;genos multirresistentes relacionados con la colonizaci&#243;n e infecci&#243;n en UCI&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Desde el a&#241;o 1994 la participaci&#243;n voluntaria de distintas UCI ha sido creciente&#44; llegando en el a&#241;o 2018 a 219 unidades pertenecientes a 185 hospitales&#46; La introducci&#243;n de datos se hace mediante una aplicaci&#243;n inform&#225;tica disponible en&#58; <a href="http://hws.vhebron.net/envin-helics/">http&#58;&#47;&#47;hws&#46;vhebron&#46;net&#47;envin-helics&#47;</a>&#46; El registro ENVIN ha sido aprobado por varios comit&#233;s de &#233;ticos de investigaci&#243;n cl&#237;nica &#40;CEIC&#41; locales y auton&#243;micos&#46; No se requiere la autorizaci&#243;n expresa de los pacientes para la utilizaci&#243;n de sus datos&#44; al ser reconocido como un registro de inter&#233;s para el Sistema Nacional de Salud &#40;a&#241;o 2014&#41;&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Se registr&#243; la presencia de neoplasia tanto hematol&#243;gica como de &#243;rgano s&#243;lido cuando esta enfermedad fue diagnostica hasta los 5 a&#241;os previos al ingreso en UCI&#44; o durante el propio ingreso&#46; Solamente en aquellos pacientes que hab&#237;an activado esta casilla se pod&#237;a completar los datos de la base ONCOENVIN&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Otros datos recogidos relativos al tama&#241;o de unidades&#44; la metodolog&#237;a del uso de dispositivos y el desarrollo de infecciones se han publicado previamente<a class="elsevierStyleCrossRefs" href="#bib0285"><span class="elsevierStyleSup">27&#8211;29</span></a> y se aportan como material electr&#243;nico suplementario&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Selecci&#243;n de pacientes base ONCOENVIN</span><p id="par0055" class="elsevierStylePara elsevierViewall">Para aquellos pacientes en los que constaba el antecedente de neoplasia &#40;como previa o como diagn&#243;stico durante el ingreso hospitalario&#41; se cumplimentaron de manera voluntaria las variables relacionadas con dicha enfermedad&#46; Se consider&#243; en primer lugar si el ingreso en UCI se deb&#237;a a causas relacionadas con la neoplasia o no&#46; En cada caso se tuvo en cuenta si la causa de ingreso era para el cuidado postoperatorio inmediato de una cirug&#237;a relacionada o no con el c&#225;ncer&#46; Entre los pacientes no quir&#250;rgicos se agrup&#243; los pacientes ingresados por complicaciones m&#233;dicas relacionadas con el c&#225;ncer&#44; que incluyeron los siguientes motivos&#58; insuficiencia respiratoria&#44; sepsis&#47;shock s&#233;ptico&#44; coma&#44; trastornos metab&#243;licos&#44; insuficiencia renal&#44; shock hemorr&#225;gico&#44; administraci&#243;n de quimioterapia u otras causas m&#233;dicas relacionadas con la neoplasia&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">En segundo lugar se diferenciaron las neoplasias hematol&#243;gicas de aquellas de &#243;rgano s&#243;lido&#46; Las neoplasias hematol&#243;gicas se separaron en linfomas&#44; leucemias y otro tipo de neoplasias malignas hematol&#243;gicas&#46; Se registr&#243; la localizaci&#243;n anat&#243;mica de los tumores s&#243;lidos&#46; Se estudi&#243; asimismo el a&#241;o en que hab&#237;a sido diagnosticada la neoplasia&#44; excluyendo todos aquellos casos previos al a&#241;o 2013&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Se tuvo en cuenta el tratamiento antineopl&#225;sico que estaban recibiendo los pacientes en el momento del ingreso en UCI&#46; Se clasificaron en tratamiento neoadyuvante &#40;terapia previa al tratamiento principal&#44; generalmente&#44; pero no siempre&#44; quir&#250;rgico&#41;&#44; tratamiento adyuvante &#40;tratamiento complementario y posterior al tratamiento principal&#41;&#44; tratamiento con intenci&#243;n radical&#44; y tratamiento con primera o sucesivas l&#237;neas frente a la enfermedad metast&#225;sica&#46; Finalmente agrupamos en tratamiento sintom&#225;tico a aquellos pacientes a los que no se les administraba ning&#250;n tratamiento activo&#44; o que recibieron solo tratamiento de soporte o puramente sintom&#225;tico &#40;por ejemplo para el dolor&#41;&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">Por otro lado&#44; tambi&#233;n se han registrado los tratamientos especialmente dirigidos frente a neoplasias hematol&#243;gicas como trasplante alog&#233;nico de m&#233;dula &#243;sea&#44; trasplante aut&#243;logo de m&#233;dula &#243;sea y quimioterapia para leucemia aguda &#40;ya fuera inducci&#243;n&#44; consolidaci&#243;n o mantenimiento&#41;&#46; Finalmente se agrup&#243; en otros tratamientos cuando no se cumpl&#237;an las definiciones previas&#44; y que puede incluir hormonoterapia&#44; quimioterapia con hipertermia intracavitaria abdominal&#44; as&#237; como tratamientos paliativos y que no recibieran ning&#250;n tratamiento espec&#237;fico antineopl&#225;sico en el momento de su ingreso en UCI&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Durante la estancia del paciente en UCI se registr&#243; el desarrollo de neutropenia &#40;menor de 500 neutr&#243;filos por mm<span class="elsevierStyleSup">3</span>&#41; que no estaba presente al ingreso en UCI&#44; la administraci&#243;n de quimioterapia durante el ingreso en UCI&#44; el s&#237;ndrome de lisis tumoral seg&#250;n criterios de Cairo y Bishop<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">30</span></a>&#44; la limitaci&#243;n de los tratamientos de soporte vital &#40;tanto de su retirada como de no inicio de un tratamiento&#41; y el diagn&#243;stico de aspergilosis pulmonar &#40;datos cl&#237;nicos compatibles m&#225;s galactomanano s&#233;rico o en lavado broncoalveolar o por cultivo de <span class="elsevierStyleItalic">Aspergillus</span> spp&#46; en muestra respiratoria&#41;&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">An&#225;lisis estad&#237;stico</span><p id="par0080" class="elsevierStylePara elsevierViewall">Ambas bases&#44; que estaban alojadas en servidores distintos &#40;servidores de Hospital Vall d&#8217;Hebron y SEMICYUC respectivamente&#41;&#44; fueron fusionadas utilizando el identificador com&#250;n que no permit&#237;a la identificaci&#243;n del paciente&#46; Las variables cualitativas se expresan como porcentaje y las variables cuantitativas como media y desviaci&#243;n est&#225;ndar o como mediana y rango intercuart&#237;lico &#40;p25-p75&#41; cuando la variable no segu&#237;a una distribuci&#243;n normal&#46; El an&#225;lisis bivariante se realiz&#243; mediante el test de Chi cuadrado para variables cualitativas y de Mann-Whitney &#40;2 muestras&#41; o Kruskall-Wallis &#40;m&#225;s de 2 muestras&#41; para las cuantitativas&#46; No se realiz&#243; un an&#225;lisis de los factores relacionados con la mortalidad&#44; pero se estudi&#243; la mortalidad en UCI relacionada con el tiempo mediante curvas de Kaplan-Meier aplicadas a la poblaci&#243;n general y a la diferenciaci&#243;n seg&#250;n el motivo de ingreso y su relaci&#243;n con el c&#225;ncer&#46; Se censur&#243; el alta&#47;exitus a los 60 d&#237;as de estancia en UCI&#46; Para todos los an&#225;lisis se consider&#243; significativo una p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#46; El an&#225;lisis estad&#237;stico se realiz&#243; mediante el paquete estad&#237;stico SPSS de IBM en su versi&#243;n 23&#46;0&#46;</p></span></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Resultados</span><p id="par0085" class="elsevierStylePara elsevierViewall">En el a&#241;o 2018 se registraron en el periodo ENVIN completo &#40;abril-junio&#41; 27&#46;514 pacientes ingresados en alguna de las 219 unidades que participaron ese a&#241;o en el registro&#46; Un total de 4&#46;247 &#40;15&#44;4&#37;&#41; pacientes cumpl&#237;an el antecedente de neoplasia&#46; De ellos el 60&#37; de los casos &#40;2&#46;547 pacientes&#41; dispon&#237;a de los datos completos de la base ONCOENVIN&#46; Puesto que la participaci&#243;n era voluntaria y abierta&#44; se consider&#243; que aquellas unidades que hab&#237;an introducido en ONCOENVIN menos del 80&#37; de los casos que se hab&#237;an declarado en ENVIN deb&#237;an ser excluidos&#46; Hubo 92 unidades que completaron m&#225;s del 80&#37; de los casos&#44; por lo que sus datos se consideran v&#225;lidos para el estudio epidemiol&#243;gico&#46; Ciento veintid&#243;s &#40;5&#44;7&#37;&#41; pacientes de estas unidades con intenci&#243;n de participar no ten&#237;an los datos oncol&#243;gicos&#46; Por otro lado&#44; 238 pacientes fueron excluidos por criterios de mala identificaci&#243;n de la fecha de diagn&#243;stico de la neoplasia o por edad inferior a 18 a&#241;os&#46; Finalmente se estudian 1&#46;786 pacientes con neoplasia y registro completo &#40;42&#37; de los pacientes con neoplasia&#41; frente a 10&#46;010 pacientes sin neoplasia pertenecientes a las unidades con intenci&#243;n de participar &#40;43&#37; de los pacientes sin neoplasia&#41;&#46; Por lo tanto&#44; en esta poblaci&#243;n seleccionada los pacientes oncol&#243;gicos constituyen el 15&#44;1&#37; del total de pacientes&#46; En la <a class="elsevierStyleCrossRef" href="#fig0005">figura 1</a> se representa el proceso de selecci&#243;n de pacientes para el estudio epidemiol&#243;gico&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0090" class="elsevierStylePara elsevierViewall">El porcentaje de pacientes oncol&#243;gicos con respecto al total de ingresos en las 92 unidades seleccionadas es muy variable&#44; con una mediana de 17 pacientes &#40;p25-p75&#58; 10-24&#44;5&#41; por unidad&#44; pero con una proporci&#243;n que oscila entre el 1&#37; y el 48&#37; de pacientes oncol&#243;gicos con respecto al total por unidad&#46; Esta variaci&#243;n expresa la diversidad de las caracter&#237;sticas de las UCI participantes&#44; en la que se incluyeron unidades coronarias &#40;con un porcentaje de pacientes oncol&#243;gicos obviamente muy bajo&#41; y unidades posquir&#250;rgicas de peque&#241;o tama&#241;o con porcentajes de pacientes oncol&#243;gicos muy elevados&#46; En conjunto&#44; el 87&#37; de las unidades se consideraban polivalentes&#44; con un 3&#44;3&#37; de unidades exclusivamente posquir&#250;rgicas y la misma proporci&#243;n de unidades de pacientes traumatizados&#46; Hab&#237;a una distribuci&#243;n geogr&#225;fica uniforme&#44; estando representadas todas las comunidades aut&#243;nomas y un total de 38 provincias&#46;</p><p id="par0095" class="elsevierStylePara elsevierViewall">En comparaci&#243;n con los pacientes sin neoplasia&#44; aquellos que tuvieron entre sus antecedentes pr&#243;ximos el diagn&#243;stico de neoplasia fueron en general pacientes mayores&#44; procedentes de plantas de hospitalizaci&#243;n&#44; con predominio de antecedente quir&#250;rgico&#44; con mayor gravedad al ingreso&#44; con estancia m&#225;s corta y con una mortalidad en UCI mayor &#40;12&#44;3&#37; versus 8&#44;5&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Estos datos se muestran en la <a class="elsevierStyleCrossRef" href="#tbl0005">tabla 1</a>&#46; Las curvas de Kaplan-Meier que reflejan la diferencia temporal de la supervivencia se muestran en la <a class="elsevierStyleCrossRef" href="#fig0010">figura 2</a> &#40;Log-Rank test p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0100" class="elsevierStylePara elsevierViewall">Por hacer una aproximaci&#243;n hacia el tipo de paciente ingresado en UCI&#44; y teniendo en cuenta la prevalencia de pacientes quir&#250;rgicos entre los pacientes oncol&#243;gicos&#44; se ha hecho una distribuci&#243;n seg&#250;n los pacientes tuvieran proceso patol&#243;gico m&#233;dico &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>585&#41;&#44; o fueran ingresados tras cirug&#237;a programada &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>834&#41; o tras cirug&#237;a urgente &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>273&#41;&#46; Se excluyen los pacientes coronarios y traumatol&#243;gicos por su escasa representaci&#243;n &#40;5&#44;2&#37; en conjunto&#41; y por no tener influencia para el objetivo del estudio&#46; En general&#44; los pacientes con enfermedad de base m&#233;dica fueron m&#225;s graves&#44; con mayores porcentajes de comorbilidades y de complicaciones infecciosas y con una mortalidad significativamente mayor &#40;27&#37;&#41; que los pacientes quir&#250;rgicos programados &#40;2&#37;&#41; o quir&#250;rgicos urgentes &#40;13&#44;2&#37;&#41;&#46; El resto de las caracter&#237;sticas diferenciales puede observarse en la <a class="elsevierStyleCrossRef" href="#tbl0010">tabla 2</a>&#46; Obviamente&#44; los pacientes hematol&#243;gicos ingresaron con mayor frecuencia por causas m&#233;dicas &#40;89&#44;6&#37;&#41; que por causas quir&#250;rgicas programadas &#40;3&#44;3&#37;&#41; o urgentes &#40;7&#44;1&#37;&#41;&#46; Por el contrario&#44; los pacientes con neoplasia de &#243;rganos s&#243;lidos ingresaron m&#225;s por causas quir&#250;rgicas en conjunto &#40;72&#44;1&#37;&#41; que m&#233;dicas &#40;27&#44;9&#37;&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0105" class="elsevierStylePara elsevierViewall">Otra forma de abordaje epidemiol&#243;gico es tener en cuenta el motivo de ingreso en relaci&#243;n con la propia neoplasia&#46; Se dividen en 3 grupos&#58; no relacionado con el c&#225;ncer &#40;NRC&#41; n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>400&#59; posquir&#250;rgico relacionado con el c&#225;ncer &#40;PRC&#41; n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1&#46;006 y complicaciones m&#233;dicas relacionadas con el c&#225;ncer &#40;CMRC&#41; n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>379&#44; con la inclusi&#243;n de pacientes seg&#250;n lo descrito en la metodolog&#237;a&#46; Este &#250;ltimo grupo estuvo formado por pacientes m&#225;s j&#243;venes&#44; de mayor gravedad&#44; con enfermedad de base predominantemente m&#233;dica y con un porcentaje alto de utilizaci&#243;n de dispositivos como ventilaci&#243;n mec&#225;nica &#40;46&#44;2&#37;&#41; o depuraci&#243;n extrarrenal &#40;9&#44;2&#37;&#41;&#46; En la <a class="elsevierStyleCrossRef" href="#tbl0015">tabla 3</a> se describe las caracter&#237;sticas de estos pacientes&#44; incluyendo localizaci&#243;n de la neoplasia&#44; el a&#241;o del diagn&#243;stico del c&#225;ncer y el tratamiento antineopl&#225;sico recibido&#44; destacando la ausencia de tratamiento hasta el momento del ingreso en la mayor&#237;a de pacientes PRC &#40;49&#44;5&#37;&#41;&#46; Por el contrario&#44; haber recibido otros tratamientos distintos a los grupos anteriores es m&#225;s frecuente en aquellos pacientes ingresados por motivos NRC &#40;41&#44;5&#37;&#41;&#46; La neutropenia durante el ingreso&#44; la quimioterapia en UCI o el s&#237;ndrome de lisis tumoral son m&#225;s frecuentes en pacientes ingresados por CMRC&#46; En este &#250;ltimo grupo es llamativa la proporci&#243;n de pacientes en los que se lleva a cabo alguna forma de limitaci&#243;n del esfuerzo terap&#233;utico &#40;17&#44;2&#37;&#41; frente a los otros grupos &#40;NRC&#58; 5&#44;8&#37; y PRC&#58; 1&#44;5&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Una probable aspergilosis se diagnostic&#243; en el 2&#44;9&#37; de los pacientes ingresados por CMRC&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0110" class="elsevierStylePara elsevierViewall">La estancia en UCI de los pacientes ingresados por CMRC fue superior a los otros grupos&#44; as&#237; como la mortalidad en UCI &#40;31&#44;4&#37;&#41;&#44; que fue significativamente m&#225;s alta que la de los pacientes ingresados por NRC &#40;12&#44;8&#37;&#41; o PRC &#40;5&#37;&#41; &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Desde el punto de vista de la supervivencia global los pacientes ingresados por CMRC se diferenciaron claramente de los otros 2 grupos &#40;Log-Rank test<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; como se observa en las curvas de Kaplan-Meier que se representan en la <a class="elsevierStyleCrossRef" href="#fig0015">figura 3</a>&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Discusi&#243;n</span><p id="par0115" class="elsevierStylePara elsevierViewall">En el presente trabajo se describe por primera vez en Espa&#241;a la epidemiolog&#237;a de los pacientes con neoplasia de &#243;rgano s&#243;lido o hematol&#243;gica que requieren ingreso en las UCI&#46; Un 15&#37; de los pacientes ingresados en UCI padecen una neoplasia&#44; pero es remarcable la diversidad en esta proporci&#243;n dependiendo del tipo de unidad&#44; lo que representa la heterogeneidad de las unidades de cr&#237;ticos espa&#241;olas&#46; La realizaci&#243;n de este estudio multic&#233;ntrico&#44; tomando como base las unidades participantes en el registro ENVIN&#44; ha permitido obtener una imagen muy precisa del <span class="elsevierStyleItalic">case-mix</span> de los pacientes con neoplasia ingresados en las UCI&#44; tanto por el n&#250;mero de unidades participantes como por la distribuci&#243;n geogr&#225;fica&#46; Ninguna de las UCI participantes era una unidad monogr&#225;fica de pacientes con c&#225;ncer&#46; El car&#225;cter multic&#233;ntrico y voluntario del registro ha condicionado que no todas las UCI participantes en el registro ENVIN hayan completado los datos de los pacientes oncol&#243;gicos y no se hayan registrado todos los pacientes posibles&#46; La utilizaci&#243;n de un criterio arbitrario de tener el registro completo de al menos el 80&#37; de los pacientes con neoplasia reduce el n&#250;mero de UCI participantes&#44; pero en nuestra opini&#243;n nos acerca bastante a la realidad epidemiol&#243;gica de los pacientes oncol&#243;gicos que requieren ingreso en UCI en nuestro pa&#237;s&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">Aunque no es el objetivo de este estudio analizar los factores relacionados con la mortalidad &#40;que ser&#225; analizado en otro art&#237;culo&#41;&#44; el fallecimiento en UCI de los pacientes con neoplasia es significativamente superior al de los pacientes sin neoplasia &#40;12&#44;3&#37; versus 8&#44;5&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; Sin embargo&#44; por la heterogeneidad de los pacientes oncol&#243;gicos el dato dice poco sobre las causas que influyen en ella&#46; Las curvas de Kaplan-Meier reflejan bien la diferencia de mortalidad&#44; pero no representan m&#225;s que un momento &#40;la estancia en UCI&#41; de la evoluci&#243;n de la enfermedad neopl&#225;sica&#44; por lo que se les debe dar el valor real que tienen en relaci&#243;n con el n&#250;mero de altas de UCI de pacientes vivos&#46; No se dispone de datos de mortalidad hospitalaria &#40;por no ser obligatorio para el registro ENVIN&#41;&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">Entre los pacientes con neoplasia&#44; los que ingresan para cuidado postoperatorio constituyen el 62&#37; del total&#44; el mismo porcentaje que el encontrado en la serie europea derivada del estudio SOAP<a class="elsevierStyleCrossRef" href="#bib0230"><span class="elsevierStyleSup">16</span></a>&#44; y similar a los estudios multic&#233;ntricos holand&#233;s<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">18</span></a> y brasile&#241;o<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a> &#40;56&#37; y 64&#37; respectivamente&#41;&#46; En este grupo de pacientes&#44; igual que lo que ocurre en el conjunto de los pacientes cr&#237;ticos<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">29</span></a>&#44; se diferencian aquellos ingresados en el postoperatorio de forma programada &#40;menor gravedad&#44; estancia y mortalidad&#41; de aquellos ingresados tras cirug&#237;a urgente&#44; que son pacientes con mayor gravedad&#44; estancia y mortalidad que es intermedia entre los quir&#250;rgicos programados y los pacientes con enfermedad de base m&#233;dica&#46; Algunos autores optan por estudiar solamente aquellos pacientes que ingresan de manera no programada&#44; lo que permite una cierta unificaci&#243;n del <span class="elsevierStyleItalic">case-mix</span><a class="elsevierStyleCrossRefs" href="#bib0235"><span class="elsevierStyleSup">17&#44;20</span></a>&#44; si bien la diferenciaci&#243;n entre pacientes m&#233;dicos &#40;40&#44;7&#37;&#41; y quir&#250;rgicos urgentes &#40;59&#44;3&#37;&#41; sigue siendo manifiesta&#44; con peor pron&#243;stico de los primeros&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">Los pacientes ingresados por causa m&#233;dica &#40;que suponen el 34&#44;6&#37; de todos los pacientes con c&#225;ncer&#41; constituyen un grupo muy heterog&#233;neo&#44; con diferencias entre aquellos que padecen una neoplasia de &#243;rgano s&#243;lido &#40;72&#44;1&#37;&#41; de los que padecen una neoplasia hematol&#243;gica &#40;27&#44; 9&#37;&#41;&#46; La proporci&#243;n de pacientes hematol&#243;gicos ingresados en las UCI en nuestro pa&#237;s es mayor que la encontrada en otras series&#44; que oscila entre el 14&#44;6&#37; y el 17&#37;<a class="elsevierStyleCrossRefs" href="#bib0230"><span class="elsevierStyleSup">16&#44;19</span></a>&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">La mortalidad de los pacientes oncol&#243;gicos m&#233;dicos &#40;27&#44;5&#37;&#41; es claramente superior a los otros 2 grupos &#40;2&#37; y 13&#44;2&#37; para quir&#250;rgicos programados y urgentes respectivamente&#41;&#44; lo que tambi&#233;n ha sido descrito en otras series epidemiol&#243;gicas<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a>&#46; La mortalidad en UCI en la serie multic&#233;ntrica holandesa<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">17</span></a> fue 30&#44;4&#37; para pacientes m&#233;dicos y 16&#44;2&#37; para los pacientes quir&#250;rgicos&#46; Por otro lado&#44; es llamativo que la proporci&#243;n de pacientes en los que se ha realizado una estrategia de limitaci&#243;n del esfuerzo terap&#233;utico es claramente superior &#40;14&#37;&#41; en el grupo de pacientes m&#233;dicos frente a los otros grupos de pacientes&#44; lo que identifica una poblaci&#243;n de pacientes m&#225;s compleja y con enfermedad aguda m&#225;s grave&#46; Ser&#237;a interesante estudiar la influencia que tiene el estadio de la enfermedad neopl&#225;sica en esta decisi&#243;n&#46;</p><p id="par0140" class="elsevierStylePara elsevierViewall">Tiene inter&#233;s describir cu&#225;les son los motivos de ingreso en UCI y su relaci&#243;n con el c&#225;ncer&#46; Entre los pacientes quir&#250;rgicos esta relaci&#243;n es alta &#40;94&#44;2&#37; de los programados y 76&#44;6&#37; de los urgentes&#41;&#44; mientras que entre los pacientes m&#233;dicos esta relaci&#243;n es menor&#44; con un alto porcentaje de pacientes que ingresan por motivos no directamente relacionados con el c&#225;ncer &#40;38&#37;&#41; y que representan los procesos intercurrentes&#44; que ocurren tanto en el paciente oncol&#243;gico como en la poblaci&#243;n no oncol&#243;gica&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">La insuficiencia respiratoria &#40;38&#44;5&#37;&#41; y la sepsis&#47;shock s&#233;ptico &#40;36&#44;4&#37;&#41; son las causas m&#225;s frecuentes de ingreso en UCI por CMRC&#46; Este dato no es sorprendente&#44; puesto que el empleo de ventilaci&#243;n mec&#225;nica invasiva es m&#225;s frecuente en este grupo de pacientes&#44; y probablemente lo sea el empleo de vasopresores &#40;que no se ha registrado en este estudio&#41;&#44; pero es com&#250;n en las series publicadas<a class="elsevierStyleCrossRefs" href="#bib0230"><span class="elsevierStyleSup">16&#44;19&#44;21</span></a>&#46; El conjunto de los pacientes que ingresan por motivos relacionados con el c&#225;ncer tiene una mortalidad del 31&#44;4&#37;&#44; lo que demuestra la importancia de los fallos org&#225;nicos en la evoluci&#243;n de estos pacientes&#44; que constituyen un subgrupo de pacientes especiales por su elevada mortalidad y consumo de recursos y sobre los que se debate acerca de la posible futilidad de su ingreso&#46;</p><p id="par0150" class="elsevierStylePara elsevierViewall">Con respecto al tratamiento oncol&#243;gico recibido antes del ingreso en UCI&#44; es llamativo el alto porcentaje de tratamientos sintom&#225;ticos &#40;17&#44;8&#37;&#41; u otros tratamientos &#40;41&#44;5&#37;&#41; entre aquellos pacientes que ingresan por motivos no relacionados con el c&#225;ncer&#46; Es posible que estos pacientes est&#233;n encuadrados en 2 extremos&#44; aquellos que reciben tratamientos paliativos o aquellos libres de enfermedad activa y que no est&#233;n recibiendo tratamientos espec&#237;ficos e ingresen en UCI por motivos bien distintos&#46;</p><p id="par0155" class="elsevierStylePara elsevierViewall">Las limitaciones de esta investigaci&#243;n son varias&#58; valorar el estadio de la neoplasia y evaluar la influencia a la hora de tomar o no decisiones terap&#233;uticas resulta complejo&#46; Aunque se ha intentado abarcar todas las posibilidades terap&#233;uticas como una continuidad desde el paciente pendiente de inicio de tratamiento hasta el tratamiento de la enfermedad metast&#225;sica&#44; este aspecto no es f&#225;cil de definir en el momento puntual que significa el ingreso en UCI&#46; Quiz&#225; definiciones m&#225;s sencillas para el tipo de c&#225;ncer &#40;local o metast&#225;sico para neoplasias de &#243;rgano s&#243;lido&#59; alto o bajo grado de malignidad para las hematol&#243;gicas&#41; hubiera permitido agrupar m&#225;s los pacientes y analizarlos m&#225;s f&#225;cilmente<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">19</span></a>&#44; pero siempre quedar&#237;a un porcentaje de pacientes en los que no fuera posible determinar el estadio evolutivo de su enfermedad&#46; Hay que considerar tambi&#233;n que lo que se ha recogido es la mortalidad en UCI&#44; no la mortalidad hospitalaria o la mortalidad a los 90 d&#237;as&#44; que para el curso de la enfermedad neopl&#225;sica hubiera sido m&#225;s correcto&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">El porcentaje de pacientes con neoplasia e infecciones nosocomiales&#44; incluyendo aspergilosis&#44; ha sido escaso en todos los grupos analizados&#44; si bien no se han calculado las tasas relacionadas con el uso de dispositivos que favorece la infecci&#243;n &#40;como se registra en el ENVIN&#41;&#44; por lo que no se puede llegar a conclusiones al respecto&#46; No parece que las infecciones nosocomiales en estos pacientes constituya un problema muy diferente de la poblaci&#243;n general no neopl&#225;sica&#46;</p><p id="par0165" class="elsevierStylePara elsevierViewall">La elecci&#243;n de 5 a&#241;os como limitaci&#243;n en la definici&#243;n de c&#225;ncer como antecedente personal no deja de ser arbitraria&#46; Es posible que algunos de estos pacientes est&#233;n &#171;curados&#187; de su neoplasia en el momento del ingreso en UCI&#46; Se ha adoptado esta definici&#243;n porque es la empleada en el ENVIN y por las dificultades que puede tener decidir la curaci&#243;n o no de una neoplasia en pacientes que ingresan por otros motivos&#46; Tambi&#233;n resulta complejo determinar si los motivos de ingreso en UCI tienen que ver o no con la neoplasia&#46; Parece evidente en los extremos &#40;posquir&#250;rgico o un shock s&#233;ptico en un paciente con neutropenia profunda posquimioterapia&#41;&#44; pero puede no serlo tanto en pacientes intermedios&#46; Por otro lado&#44; en las m&#250;ltiples comparaciones realizadas se han encontrado diferencias estad&#237;sticamente significativas como consecuencia del tama&#241;o muestral&#46; Algunas de esas diferencias tienen poco significado cl&#237;nico y requerir&#237;an an&#225;lisis <span class="elsevierStyleItalic">post-hoc</span> m&#225;s detallados&#46;</p><p id="par0170" class="elsevierStylePara elsevierViewall">En conclusi&#243;n&#44; en este trabajo multic&#233;ntrico se presenta la epidemiolog&#237;a de los pacientes con antecedentes oncol&#243;gicos cercanos o cuyo motivo de ingreso es para el tratamiento de la neoplasia o sus complicaciones&#46; Existe una gran variabilidad en el porcentaje de pacientes oncol&#243;gicos en las diferentes UCI del pa&#237;s&#44; con un predominio de pacientes posquir&#250;rgicos programados &#40;46&#44;7&#37;&#41;&#46; La mortalidad global de los pacientes con neoplasia es el 12&#44;3&#37;&#44; pero se identifica una poblaci&#243;n de pacientes m&#225;s graves y con mayor mortalidad&#46; En concreto&#44; la mortalidad de los pacientes con enfermedad de base m&#233;dica es del 27&#44;5&#37;&#44; y la de aquellos pacientes que ingresan por complicaciones m&#233;dicas relacionadas con el c&#225;ncer es a&#250;n superior&#44; el 31&#44;4&#37;&#46; Es necesario hacer estudios sobre los factores relacionados con la mortalidad&#44; de manera m&#225;s espec&#237;fica&#44; en estas poblaciones&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0130">Autor&#237;a</span><p id="par0175" class="elsevierStylePara elsevierViewall">PMOA&#44; FAL y RGC son coordinadores del registro ENVIN&#46; JGM&#44; FGV y CBZ forman parte del grupo de trabajo colaborativo SEMICYUC-SEOM&#46; RDN&#44; CRS e IAA son investigadoras principales de sus hospitales y han contribuido con un mayor n&#250;mero de casos&#46; EL dise&#241;o del estudio ha sido realizado por el grupo de trabajo SEMICYUC-SEOM&#46; La redacci&#243;n ha sido realizada por PMOA y corregida por el resto de los autores&#44; que est&#225;n de acuerdo con su contenido&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0135">Financiaci&#243;n</span><p id="par0180" class="elsevierStylePara elsevierViewall">El registro ENVIN-HELICS ha sido financiado parcialmente durante el a&#241;o 2018 por la Agencia Espa&#241;ola del Medicamento y Productos Sanitarios &#40;AEMPS&#41;&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0140">Conflicto de intereses</span><p id="par0185" class="elsevierStylePara elsevierViewall">Los autores declaran no tener ning&#250;n conflicto de intereses con respecto al contenido de este manuscrito&#46;</p></span></span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Conocer la epidemiolog&#237;a y evoluci&#243;n al alta de los pacientes oncol&#243;gicos que precisan ingreso en UCI&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Dise&#241;o</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Estudio descriptivo observacional de datos del registro ENVIN-HELICS combinado con variables registradas espec&#237;ficamente&#46; Se comparan pacientes con y sin neoplasia&#46; Se identifican grupos de pacientes neopl&#225;sicos con peor evoluci&#243;n&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">&#193;mbito</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">UCI participantes en ENVIN-HELICS del a&#241;o 2018 con participaci&#243;n voluntaria en el registro oncol&#243;gico&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Pacientes</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Ingresados m&#225;s de 24<span class="elsevierStyleHsp" style=""></span>horas&#46; Entre estos aquellos diagnosticados de neoplasia en los &#250;ltimos 5 a&#241;os&#46;</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Variables principales</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Las generales epidemiol&#243;gicas del registro ENVIN-HELICS y variables relacionadas con la neoplasia&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Resultados</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">En las 92 UCI con datos completos se seleccionaron 11&#46;796 pacientes&#44; de los que 1&#46;786 &#40;15&#44;1&#37;&#41; son pacientes con neoplasia&#46; La proporci&#243;n de pacientes con c&#225;ncer por unidad fue muy variable &#40;rango&#58; 1-48&#37;&#41;&#46; La mortalidad en UCI de los pacientes oncol&#243;gicos fue superior a los no oncol&#243;gicos &#40;12&#44;3&#37; versus 8&#44;9&#37;&#59; p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41;&#46; En pacientes oncol&#243;gicos predominaron los ingresados en el postoperatorio programado &#40;46&#44;7&#37;&#41; o urgente &#40;15&#44;3&#37;&#41;&#46; Los pacientes con proceso patol&#243;gico m&#233;dico fueron m&#225;s graves&#44; con mayor estancia y mortalidad &#40;27&#44; 5&#37;&#41;&#46; Aquellos ingresados en UCI por enfermedad no quir&#250;rgica relacionada con el c&#225;ncer tuvieron la mortalidad m&#225;s alta &#40;31&#44;4&#37;&#41;&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conclusi&#243;n</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Existe una gran variabilidad en el porcentaje de pacientes oncol&#243;gicos en las diferentes UCI&#46; El 46&#44;7&#37; de los pacientes ingresa tras someterse a cirug&#237;a programada&#46; La mayor mortalidad corresponde a pacientes con enfermedad m&#233;dica &#40;27&#44;5&#37;&#41; y a los ingresados por complicaciones relacionadas con el c&#225;ncer &#40;31&#44;4&#37;&#41;&#46;</p></span>"
        "secciones" => array:7 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objetivo"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Dise&#241;o"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "&#193;mbito"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Pacientes"
          ]
          4 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Variables principales"
          ]
          5 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "Resultados"
          ]
          6 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Conclusi&#243;n"
          ]
        ]
      ]
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Objective</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">To assess the epidemiology and outcome at discharge of cancer patients requiring admission to the Intensive Care Unit &#40;ICU&#41;&#46;</p></span> <span id="abst0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Design</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">A descriptive observational study was made of data from the ENVIN-HELICS registry&#44; combined with specifically compiled variables&#46; Comparisons were made between patients with and without neoplastic disease&#44; and groups of cancer patients with a poorer outcome were identified&#46;</p></span> <span id="abst0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Setting</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Intensive Care Units participating in ENVIN-HELICS 2018&#44; with voluntary participation in the oncological registry&#46;</p></span> <span id="abst0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Patients</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Subjects admitted during over 24<span class="elsevierStyleHsp" style=""></span>hours and diagnosed with cancer in the last 5 years&#46;</p></span> <span id="abst0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Primary endpoints</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">The general epidemiological endpoints of the ENVIN-HELICS registry and cancer-related variables&#46;</p></span> <span id="abst0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Of the 92 ICUs with full data&#44; a total of 11&#44;796 patients were selected&#44; of which 1786 &#40;15&#46;1&#37;&#41; were cancer patients&#46; The proportion of cancer patients per Unit proved highly variable &#40;1-48&#37;&#41;&#46; In-ICU mortality was higher among the cancer patients than in the non-oncological subjects &#40;12&#46;3&#37; versus 8&#46;9&#37;&#59; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;001&#41;&#46; Elective postoperative &#40;46&#46;7&#37;&#41; or emergency admission &#40;15&#46;3&#37;&#41; predominated in the cancer patients&#46; Patients with medical disease were in more serious condition&#44; with longer stay and greater mortality &#40;27&#46;5&#37;&#41;&#46; The patients admitted in ICU due to nonsurgical disease related to cancer exhibited the highest mortality rate &#40;31&#46;4&#37;&#41;&#46;</p></span> <span id="abst0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Conclusions</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Great variability was recorded in the percentage of cancer patients in the different ICUs&#46; A total of 46&#46;7&#37; of the patients were admitted after undergoing scheduled surgery&#46; The highest mortality rate corresponded to patients with medical disease &#40;27&#46;5&#37;&#41;&#44; and to those admitted due to cancer-related complications &#40;31&#46;4&#37;&#41;&#46;</p></span>"
        "secciones" => array:7 [
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            "titulo" => "Objective"
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            "identificador" => "abst0045"
            "titulo" => "Design"
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          2 => array:2 [
            "identificador" => "abst0050"
            "titulo" => "Setting"
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          3 => array:2 [
            "identificador" => "abst0055"
            "titulo" => "Patients"
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          4 => array:2 [
            "identificador" => "abst0060"
            "titulo" => "Primary endpoints"
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          5 => array:2 [
            "identificador" => "abst0065"
            "titulo" => "Results"
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          6 => array:2 [
            "identificador" => "abst0070"
            "titulo" => "Conclusions"
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        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:3 [
        "etiqueta" => "&#9674;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0010">En el <a class="elsevierStyleCrossRef" href="#sec0055">anexo 1</a> figura el listado de responsables y unidades participantes en estudio ONCOENVIN ordenados por n&#250;mero de pacientes aportados al estudio epidemiol&#243;gico&#46;</p>"
        "identificador" => "fn0005"
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            "apendice" => "<p id="par0195" class="elsevierStylePara elsevierViewall">Raquel Dur&#225; Navarro&#44; Hospital General Universitario de Valencia &#40;U&#46; Polivalente&#41;&#46; Mar&#237;a Carmen Ruano Suarez&#44; Hospital de Cruces &#40;U&#46; Reanimaci&#243;n&#41;&#44; Baracaldo&#44; Vizcaya&#46; Inmaculada Alonso Araujo&#44; Hospital General Virgen del Roc&#237;o&#44; Sevilla&#46; &#193;ngel Arenzana Seisdedos&#44; Hospital Universitario Virgen Macarena&#44; Sevilla&#46; Alberto C&#243;rdoba L&#243;pez&#44; Complejo Hospitalario Universitario de Badajoz &#40;UCI 1&#41;&#46; Nuria Camino Redondo&#44; Hospital de Torrej&#243;n&#44; Torrejon de Ardoz&#44; Madrid&#46; Sandra Barbadillo Ansorregui&#44; Hospital General de Catalunya&#44; Sant Cugat del Vall&#233;s&#44; Barcelona&#46; Lorena Mouriz Fern&#225;ndez&#44; Hospital Universitario Lucus Augusti &#40;U&#46; Reanimaci&#243;n&#41;&#44; Lugo&#46; Maria Elena Vilas Otero&#44; Complexo Hospitalario Universitario de Vigo H&#46; &#193;lvaro Cunqueiro &#40;REA 2&#41;&#44; Vigo&#46; Jos&#233; Antonio M&#225;rquez Alonso&#44; Hospital Rey Juan Carlos&#44; M&#243;stoles&#44; Madrid&#46; Adoraci&#243;n Gema Bueno Bl&#225;zquez&#44; Cl&#237;nica Moncloa&#44; Madrid&#46; Ana Abella Alvarez&#44; Hospital del Henares&#44; Coslada&#44; Madrid&#46; Joaqu&#237;n Lobo Palanco&#44; Complejo Hospitalario de Navarra &#40;UCI-A&#41;&#44; Pamplona&#46; Luis Cofi&#241;o Casta&#241;eda&#44; Hospital Universitario Central de Asturias &#40;U&#46; Polivalente&#41;&#44; Oviedo&#44; Asturias&#46; J&#46;C&#46; Montejo Gonz&#225;lez&#44; Hospital Universitario 12 de Octubre&#44; U&#46; Polivalente&#44; Madrid&#46; Miguel &#193;ngel Garc&#237;a Garc&#237;a&#44; Hospital de Sagunto&#44; Valencia&#46; Mar&#237;a Dolores Sandar N&#250;&#241;ez&#44; Hospital Jerez de la Frontera&#44; C&#225;diz&#46; Mar&#237;a Teresa Tebar Soto&#44; Hospital de Basurto&#44; U&#46; Polivalente&#44; Bilbao&#44; Vizcaya&#46; Rafael Cabadas Avi&#243;n&#44; Hospital Povisa&#44; Vigo&#44; Pontevedra&#46; Ricardo Gimeno Costa&#44; Hospital Universitario y Polit&#233;cnico La Fe &#40;U&#46; M&#233;dica&#41;&#44;Valencia&#46; Jos&#233; &#193;ngel Berezo Garc&#237;a&#44; Hospital Universitario R&#237;o Hortega&#44; Valladolid&#46; Fernando Garc&#237;a L&#243;pez&#44; Hospital General Universitario de Albacete&#46; Blanca L&#243;pez Matamala&#44; Hospital Universitario del Tajo&#44; Aranjuez&#44; Madrid&#46; Asunci&#243;n Colomar Ferr&#225;&#44; Hospital Universitario Son Espases&#44; Palma de Mallorca&#46; Mar&#237;a Sopetr&#225;n Rey Garc&#237;a&#44; Complejo Asistencial de Segovia&#46; Bel&#233;n Cidoncha Calder&#243;n&#44; Hospital Don Benito-Villanueva&#44; Badajoz&#46; Sara Alc&#225;ntara Carmona&#44; Hospital Universitario Puerta de Hierro Majadahonda&#44; Madrid&#46; Eva Manteiga Riestra&#44; Hospital Infanta Cristina&#44; Parla&#44; Madrid&#46; Bernardo Gil Rueda&#44; Hospital General Universitario Morales Meseguer&#44; Murcia&#46; Carlos Gallego Gonz&#225;lez&#44; Hospital Militar G&#243;mez Ulla&#44; Madrid&#46; Roberto Jim&#233;nez S&#225;nchez&#44; Hospital General Universitario Santa Luc&#237;a&#44; Cartagena&#44; Murcia&#46; Ismael L&#243;pez de Toro Mart&#237;n-Consuegra&#44; Hospital Virgen de la Salud &#40;U&#46; Polivalente&#41;&#44; Toledo&#46; Jessica Souto Higueras&#44; Hospital Sanitas CIMA de Barcelona&#46; Arantxa Lander Azcona&#44; Hospital General San Jorge&#44; Huesca&#46; Jos&#233; Mar&#237;a Fuster Lozano&#44; Cl&#237;nica Vistahermosa&#44; HLA Grupo Hospitalario&#44; Alicante&#46; Paula Vera Art&#225;zcoz&#44; Hospital de Sant Pau &#40;U&#46; Polivalente&#41;&#44; Barcelona&#46; Mar&#237;a Jos&#233; Castro Orjales&#44; Complejo Hospitalario Universitario de Ferrol&#46; H&#46; Arquitecto Marcide&#44; La Coru&#241;a&#46; Mar&#237;a Jos&#233; Asensio Mart&#237;n&#44; Hospital Universitario La Paz &#40;U&#46; Polivalente&#41;&#44; Madrid&#46; Mar&#237;a Antonia Estecha Foncea&#44; Hospital Universitario Virgen de la Victoria&#44; M&#225;laga&#46; Roberto Reig Valero&#44; Hospital General de Castell&#243;n&#46; Jes&#250;s Priego Sanz&#44; Complexo Hospitalario Universitario de Ourense &#40;U&#46; Polivalente&#41;&#44; Susana Sancho Chinesta&#44; Hospital Doctor Peset&#44; Valencia&#46; Jordi Vall&#233;s Daunis&#44; Hospital Parc Tauli&#44; Sabadell&#44; Barcelona&#46; Ana Isabel Ezpeleta Galindo&#44; Hospital Royo Villanova&#44; Zaragoza&#46; Braulio &#193;lvarez Mart&#237;nez&#44; Hospital El Bierzo&#44; Ponferrada&#44; Le&#243;n&#46; Felipe Bobillo de Lamo&#44; Hospital Cl&#237;nico Universitario de Valladolid&#44; U&#46; Polivalente&#46; Antoni Margarit Ribas&#44; Hospital Nuestra Se&#241;ora de Meritxell&#44; Escaldes-Engordany&#44; Andorra&#46; Pedro M&#46; Olaechea Astigarraga&#44; Hospital de Galdakao &#40;U&#46; Polivalente&#41;&#44; Vizcaya&#46; Juan Carlos Ballesteros Herr&#225;ez&#44; Hospital Cl&#237;nico de Salamanca&#46; Mar&#237;a Teresa Salda&#241;a Fern&#225;ndez&#44; Hospital Universitario de Fuenlabrada&#44; Madrid&#46; &#193;ngel S&#225;nchez Miralles&#44; Hospital de Sant Joan&#44; Alicante&#46; Rosario Amaya Villar&#44; Hospital de Rehabilitaci&#243;n y Traumatolog&#237;a Virgen del Roc&#237;o&#44; Sevilla&#46; Juan Fajardo L&#243;pez-Cuervo&#44; Cl&#237;nica Santa Isabel&#44; Sevilla&#46; Antonia Socias&#44; Hospital Son Ll&#224;tzer&#44; Palma de Mallorca&#46; Alfons Bonet Saris&#44; Cl&#237;nica Girona&#46; Ana Mar&#237;a D&#237;az Lamas&#44; Complexo Hospitalario Universitario de A Coru&#241;a &#40;UCI 5&#41;&#46; Jos&#233; Ram&#243;n Iruretagoyena Amiano&#44; Hospital de Cruces &#40;U&#46; Polivalente&#41;&#44; Baracaldo&#44; Vizcaya&#46; Ingrid Acosta Rivera&#44; Cl&#237;nica Ruber de Madrid&#46; Mar&#237;a Cer&#243;n Garc&#237;a&#44; Hospital Vega Baja de Orihuela&#44; Alicante&#46; Susana Moradillo Gonz&#225;lez&#44; Hospital R&#237;o Carri&#243;n&#44; Complejo Hospitalario de Palencia&#46; Paula Rodr&#237;guez Pedreira&#44; Hospital Quir&#243;nsalud&#44; Barcelona&#46; Eduardo Palencia Herrej&#243;n&#44; Hospital Infanta Leonor&#44; Madrid&#46; Carlos L&#243;pez N&#250;&#241;ez&#44; Hospital Cl&#237;nico Universitario Lozano Blesa &#40;U&#46; M&#233;dica&#41;&#44; Zaragoza&#46; Margarita Mas Lodo&#44; Hospital General&#44; M&#243;stoles&#44; Madrid&#46; Juan Carlos Pardo Talavera&#44; Hospital Quir&#243;n Murcia&#46; Mar&#237;a Luisa Mora&#44; Hospital Universitario de Canarias &#40;UPCC&#41;&#44; Santa Cruz de Tenerife&#46; Ricard Ferrer Roca&#44; Centro M&#233;dico Delfos&#44; Barcelona&#46; Eugenia de La Fuente O&#769;connor&#44; Hospital Universitario Infanta Sof&#237;a&#44; San Sebasti&#225;n de los Reyes&#44; Madrid&#46; Miguel S&#225;nchez Garc&#237;a&#44; Hospital Cl&#237;nico Universitario San Carlos &#40;U&#46; Traumatolog&#237;a&#41;&#44; Madrid&#46; Carmen Blanco Huelga&#44; Hospital Marqu&#233;s de Valdecilla &#40;UCI 1&#41;&#44; Santander&#46; Mar&#237;a &#193;ngeles Garijo Catalina&#44; Hospital Virgen de la Luz&#44; Cuenca&#46; Adoraci&#243;n Alcal&#225; L&#243;pez&#44; Hospital General Universitario de Elche&#44; Alicante&#46; Marta Ugalde Gutierrez&#44; Hospital de Cruces &#40;U&#46; Quemados&#41;&#44; Baracaldo&#44; Vizcaya&#46; Mar&#237;a Rosa Navarro Ruiz&#44; Hospital Universitario los Arcos del Mar Menor&#44; San Javier&#44; Murcia&#46; Mar&#237;a Jos&#233; Rom&#225;n Millan&#44; Hospital de la Merced&#44; Osuna&#44; Sevilla&#46; Pedro Lara Aguayo&#44; Hospital Infanta Margarita&#44; Cabra&#44; C&#243;rdoba&#46; Mar&#237;a Herreros Gonzalo&#44; Hospital La Mancha Centro&#44; Alc&#225;zar de San Juan&#44; Ciudad Real&#46; Laura Claverias Cabrera&#44; Hospital de Tortosa Verge de la Cinta&#44; Tarragona&#46; Jos&#233; Martos L&#243;pez&#44; Hospital Vithas La Salud de Granada&#46; Mar&#237;a Concepci&#243;n Valdovinos Mahave&#44; Hospital Obispo Polanco&#44; Teruel&#46; Daniel Fontaneda L&#243;pez&#44; Hospital de Le&#243;n &#40;U&#46; Polivalente&#41;&#46; Mar&#237;a Matachana Mart&#237;nez&#44; Hospital Juan Cardona&#44; Ferrol&#44; La Coru&#241;a&#46; Esther Garc&#237;a S&#225;nchez&#44; Hospital Universitario del Sureste&#44; Arganda del Rey&#44; Madrid&#46; Carmen Santarrufina Lluch&#44; Hospital Comarcal de Vinar&#242;s&#44; Castell&#243;n&#46; Rafael Garc&#233;s Gonz&#225;lez&#44; Hospital de la Ribera&#44; Alzira&#44; Valencia&#46; Sonia Gallego Lara&#44; Hospital San Juan de Dios del Aljarafe&#44; Sevilla&#46; Pilar Martinez Trivez&#44; Hospital de Barbastro&#44; Huesca&#46; Cec&#237;lia Vilanova P&#224;mies&#44; Hospital Mateu Orfila&#44; Menorca&#46; Celina Llanos Jorge&#44; Hospital Quir&#243;nsalud&#44; Santa Cruz de Tenerife&#46; Mar&#237;a Jos&#233; Asensio Mart&#237;n&#44; Hospital Universitario La Paz &#40;U&#46; Quemados&#41;&#44; Madrid&#46; Juan Carlos Montejo Gonzalez&#44; Hospital Universitario 12 de Octubre &#40;U&#46; Trauma y Emergencia&#41;&#44; Madrid&#46; Enrique Alemparte Pardavila&#44; Complexo Hospitalario Universitario A Coru&#241;a &#40;UCI 6&#41;&#46;</p>"
            "etiqueta" => "Anexo 1"
            "titulo" => "Listado de responsables y unidades participantes en estudio ONCOENVIN ordenados por n&#250;mero de pacientes aportados al estudio epidemiol&#243;gico&#46;"
            "identificador" => "sec0055"
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            "etiqueta" => "Anexo A"
            "titulo" => "Material adicional"
            "identificador" => "sec0065"
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          "es" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Diagrama de selecci&#243;n de pacientes&#46;</p>"
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          "es" => "<p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Curvas de Kaplan-Meier de supervivencia entre pacientes con o sin antecedentes de neoplasia&#46;</p>"
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          "es" => "<p id="spar0085" class="elsevierStyleSimplePara elsevierViewall">Curvas de Kaplan-Meier de supervivencia entre pacientes seg&#250;n el motivo de ingreso y su relaci&#243;n con el c&#225;ncer&#46;</p> <p id="spar0090" class="elsevierStyleSimplePara elsevierViewall">CMRC&#58; motivo de ingreso complicaciones m&#233;dicas relacionadas con el c&#225;ncer&#59; NRC&#58; motivo de ingreso no relacionado con el c&#225;ncer&#59; PRC&#58; motivo de ingreso posquir&#250;rgico relacionado con el c&#225;ncer&#46;</p>"
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          "leyenda" => "<p id="spar0100" class="elsevierStyleSimplePara elsevierViewall">APACHE&#58; Acute Physiology&#44; Age and Chronic Health Evaluation&#59; DE&#58; desviaci&#243;n est&#225;ndar&#59; ECMO&#58; oxigenaci&#243;n por membrana extracorp&#243;rea&#59; EPOC&#58; enfermedad pulmonar obstructiva cr&#243;nica&#59; SAPS&#58; Simplified Acute Physiology Score&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td-with-role" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Variable&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Neoplasia&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col">No neoplasia&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">Valor de p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>1786&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>10010&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&#40;15&#44;1&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&#40;84&#44;9&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Sexo</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Hombres&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1170 &#40;65&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6254 &#40;62&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;015&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Mujeres&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">616 &#40;34&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3756 &#40;37&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Edad</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">65&#44;2 &#40;12&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">63&#44;2 &#40;15&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Tama&#241;o hospital</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>500 camas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">900 &#40;50&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5666 &#40;56&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>200-500 camas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">712 &#40;39&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3426 &#40;34&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>200 camas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">174 &#40;9&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">918 &#40;9&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Origen paciente</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Unidad hospitalizaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1122 &#40;62&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3692 &#40;36&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Otra UCI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">27 &#40;1&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">271 &#40;2&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Comunidad&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">630 &#40;35&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5941 &#40;59&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Instituci&#243;n sociosanitaria&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7 &#40;0&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">106 &#40;1&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Enfermedad de base</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Coronaria&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">79 &#40;4&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1983 &#40;19&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>M&#233;dica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">585 &#40;32&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4882 &#40;48&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cirug&#237;a programada&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">834 &#40;46&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1558 &#40;15&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cirug&#237;a urgente&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">273 &#40;15&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">887 &#40;8&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Traumatismo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">15 &#40;0&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">700 &#40;7&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cirug&#237;a previa al ingreso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;130 &#40;63&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2866 &#40;28&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">APACHE II &#40;n</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#61;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">1&#46;639&#47;9&#46;186&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#44;9 &#40;7&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#44;2 &#40;8&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">SAPS 2 &#40;n</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#61;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">528&#47;3534&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Media &#40;DE&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">40&#44;2 &#40;19&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">36&#44;4 &#40;17&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Diagn&#243;sticos por aparatos</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cardiocirculatorio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">388 &#40;21&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">4985 &#40;50&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Respiratorio&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">349 &#40;19&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1175 &#40;11&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Digestivo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">597 &#40;33&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">877 &#40;8&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Neurol&#243;gico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">61 &#40;3&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1438 &#40;14&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Renal&#47;genitourinario&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">139 &#40;7&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">150 &#40;1&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Metab&#243;lico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9 &#40;0&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">123 &#40;1&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Hematol&#243;gico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">15 &#40;0&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18 &#40;0&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Traumatol&#243;gico&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">147 &#40;8&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">917 &#40;9&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Trasplantes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14 &#40;0&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">109 &#40;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Otros&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">66 &#40;3&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">161 &#40;1&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Comorbilidades</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Neutropenia previa al ingreso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">96 &#40;5&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">50 &#40;0&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Diabetes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">352 &#40;19&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">2513 &#40;25&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Insuficiencia renal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">172 &#40;9&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">1102 &#40;11&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;084&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Inmunosupresi&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">259 &#40;14&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">499 &#40;5&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cirrosis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">54 &#40;3&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">316 &#40;3&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;766&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>EPOC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">203 &#40;11&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1225 &#40;12&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;298&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Desnutrici&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">214 &#40;12&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">530 &#40;5&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Trasplante&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">13 &#40;0&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">126 &#40;1&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;055&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Dispositivos empleados durante el ingreso</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cat&#233;ter venoso central&#46;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1&#46;409 &#40;78&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">5808 &#40;58&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Ventilaci&#243;n mec&#225;nica invasiva&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">751 &#40;42&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">3729 &#40;37&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Sonda vesical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1&#46;649 &#40;92&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">7267 &#40;72&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Derivaci&#243;n ventricular&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">19 &#40;1&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">157 &#40;1&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;105&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Depuraci&#243;n extrarrenal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">76 &#40;4&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">467 &#40;4&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;446&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Nutrici&#243;n parenteral&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">240 &#40;13&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">424 &#40;4&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>ECMO&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1 &#40;0&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18 &#40;0&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;342&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="4" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Pacientes con infecciones nosocomiales</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Neumon&#237;a asociada a ventilaci&#243;n mec&#225;nica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">29 &#40;1&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">145 &#40;1&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;572&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Infecci&#243;n urinaria asociada a sondaje vesical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11 &#40;0&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">151 &#40;1&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">101 &#40;12&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">31 &#40;11&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " colspan="5" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Origen paciente</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Hospitalizaci&#243;n&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">369 &#40;63&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">513 &#40;61&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">207 &#40;75&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Otra UCI&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">13 &#40;2&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">6 &#40;0&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">7 &#40;2&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Comunidad&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">200 &#40;34&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">312 &#40;37&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">58 &#40;21&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Institucionalizado&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">3 &#40;0&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">3 &#40;0&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1 &#40;0&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cirug&#237;a previa al ingreso&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">87 &#40;14&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">749 &#40;89&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">259 &#40;94&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t  " colspan="5" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">APACHE II &#40;n</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#61;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">530&#47;760&#47;258&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Mediana &#40;p25-p75&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">18&#44;5 &#40;14-24&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">10&#44;0 &#40;7-14&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">16&#44;0 &#40;12-22&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">SAPS 2 &#40;n</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#61;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">200&#47;224&#47;81&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Mediana &#40;p25-p75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">47&#44;0 &#40;37-61&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">25&#44;0 &#40;18-34&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">49 &#40;39-61&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Comorbilidades</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Neutropenia previa al ingreso&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">84 &#40;14&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1 &#40;0&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">10 &#40;3&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Diabetes&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">135 &#40;23&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">133 &#40;15&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">56 &#40;20&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;003&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Insuficiencia renal&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">74 &#40;12&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">45 &#40;5&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">34 &#40;12&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Inmunosupresi&#243;n&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">181 &#40;30&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">43 &#40;5&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">25 &#40;9&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cirrosis&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">18 &#40;3&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">20 &#40;2&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">12 &#40;4&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;234&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>EPOC&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">80 &#40;13&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">84 &#40;10&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">18 &#40;6&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;005&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Desnutrici&#243;n&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">85 &#40;14&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">63 &#40;7&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">60 &#40;22&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Trasplante&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">3 &#40;0&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">3 &#40;0&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">6 &#40;2&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;006&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Dispositivos empleados durante el ingreso</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cat&#233;ter venoso central&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">465 &#40;79&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">645 &#40;77&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">255 &#40;93&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Ventilaci&#243;n mec&#225;nica invasiva&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">244 &#40;41&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">284 &#40;34&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">200 &#40;73&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Sonda vesical&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">520 &#40;88&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">804 &#40;96&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">266 &#40;97&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Derivaci&#243;n ventricular&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">5 &#40;0&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">11 &#40;1&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">3 &#40;1&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;716&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Depuraci&#243;n extrarrenal&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">40 &#40;6&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">11 &#40;1&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">21 &#40;7&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Nutrici&#243;n parenteral&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">65 &#40;11&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">65 &#40;7&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">101 &#40;37&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>ECMO&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1 &#40;0&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;075&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Pacientes con infecciones nosocomiales</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Neumon&#237;a asociada a ventilaci&#243;n mec&#225;nica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">19 &#40;3&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">6 &#40;0&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">3 &#40;1&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Infecci&#243;n urinaria asociada a sondaje vesical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5 &#40;0&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1 &#40;0&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4 &#40;1&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;025&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Bacteriemia de foco desconocido&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">3 &#40;0&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">2 &#40;0&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">2 &#40;0&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#44;490&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Bacteriemia secundaria a cat&#233;ter&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3 &#40;0&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">2 &#40;0&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">3 &#40;1&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;196&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Bacteriemia secundaria a otros focos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">11 &#40;1&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">5 &#40;0&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">3 &#40;1&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;079&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cirug&#237;a urgente durante el ingreso&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">36 &#40;6&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">35 &#40;4&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">144 &#40;52&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">N&#250;mero de antibi&#243;ticos recibidos en UCI por paciente</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Mediana &#40;p25-p75&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">2 &#40;1-4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1 &#40;0-1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">2 &#40;1-3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Estancia en UCI</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Medina &#40;p25-p75&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">5 &#40;3-9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">3 &#40;2-4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">5 &#40;3-10&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Exitus</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">161 &#40;27&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">17 &#40;2&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">36 &#40;13&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Motivo de ingreso en relaci&#243;n con el c&#225;ncer</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Relacionado con el c&#225;ncer&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">362 &#40;62&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">786 &#40;94&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">209 &#40;76&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>No relacionado con el c&#225;ncer&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">222 &#40;38&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">48 &#40;5&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">64 &#40;23&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Localizaci&#243;n del c&#225;ncer</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cabeza y cuello&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37 &#40;6&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">80 &#40;9&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13 &#40;4&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Colon&#47;recto&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">75 &#40;12&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">170 &#40;20&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">119 &#40;43&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>H&#237;gado&#47;biliar&#47;p&#225;ncreas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">29 &#40;5&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">99 &#40;11&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18 &#40;6&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Otros digestivo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">30 &#40;5&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">62 &#40;7&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">26 &#40;9&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Broncopulmonar&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">88 &#40;15&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">6 &#40;2&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Renal&#47;urinario&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">76 &#40;13&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Ginecol&#243;gico femenino&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Sistema nervioso central&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">105 &#40;12&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Leucemia&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">2 &#40;0&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Linfoma&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">72 &#40;12&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">3 &#40;0&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">6 &#40;2&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Otros hematol&#243;gicos&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">39 &#40;6&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">3 &#40;0&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">5 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Otros tipos de c&#225;ncer OS&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">27 &#40;4&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">26 &#40;3&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">5 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">A&#241;o de diagn&#243;stico del c&#225;ncer</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>2013&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">31 &#40;5&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">11 &#40;1&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">7 &#40;2&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>2014&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">42 &#40;7&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">32 &#40;3&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">8 &#40;2&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>2015&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">43 &#40;7&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">36 &#40;4&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">15 &#40;5&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>2016&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">45 &#40;7&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">43 &#40;5&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">22 &#40;8&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>2017&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">142 &#40;24&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">158 &#40;18&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">43 &#40;15&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>2018&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">282 &#40;48&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">554 &#40;66&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">178 &#40;65&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Tratamiento oncol&#243;gico del paciente al ingreso en UCI</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Pendiente de iniciar tratamiento&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Tratamiento neoadyuvante&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Tratamiento adyuvante&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Tratamiento con QT-RT e intenci&#243;n radical&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Trasplante de m&#233;dula &#243;sea alog&#233;nico&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Quimioterapia para leucemia aguda&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Quimioterapia en UCI</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Limitaci&#243;n de tratamientos de soporte vital</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Institucionalizado&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">3 &#40;0&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Cirug&#237;a previa al ingreso</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">69 &#40;18&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " colspan="5" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">APACHE II &#40;n</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#61;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">369&#47;921&#47;349&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Mediana &#40;p25-p75&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">16 &#40;11-21&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">SAPS 2 &#40;n</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">&#61;</span><span class="elsevierStyleHsp" style=""></span><span class="elsevierStyleItalic">124&#47;274&#47;130&#41;</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Mediana &#40;p25-p75&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">46 &#40;32&#44;5-61&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">28 &#40;19-40&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">48 &#40;37-63&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Enfermedad de base</span><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a></td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>M&#233;dica&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">331 &#40;90&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Quir&#250;rgica programada&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">48 &#40;13&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">781 &#40;81&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">5 &#40;1&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Quir&#250;rgica urgente&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">36 &#40;9&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Comorbilidades</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Neutropenia previa al ingreso&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">74 &#40;19&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Diabetes&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">120 &#40;30&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">70 &#40;18&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Insuficiencia renal&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">61 &#40;15&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">72 &#40;7&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">39 &#40;10&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Inmunosupresi&#243;n&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">63 &#40;15&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">64 &#40;6&#44;4&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">131 &#40;34&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cirrosis&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">17 &#40;4&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">30 &#40;3&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">7 &#40;1&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;146&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>EPOC&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">66 &#40;16&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">96 &#40;9&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">41 &#40;10&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Desnutrici&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">42 &#40;10&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">102 &#40;10&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">70 &#40;18&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Trasplante&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">3 &#40;0&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">9 &#40;0&#44;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1 &#40;0&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&#44;468&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleItalic">Dispositivos empleados durante el ingreso</span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Cat&#233;ter venoso central&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">263 &#40;65&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">816 &#40;81&#44;1&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">329 &#40;86&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Ventilaci&#243;n mec&#225;nica invasiva&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">155 &#40;38&#44;8&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">420 &#40;41&#44;7&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">175 &#40;46&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Sonda vesical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">325 &#40;81&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t">976 &#40;97&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">347 &#40;91&#44;6&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;001&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Derivaci&#243;n ventricular&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">6 &#40;1&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">12 &#40;1&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1 &#40;0&#44;3&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#44;203&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t"><span class="elsevierStyleHsp" style=""></span>Depuraci&#243;n extrarrenal&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">16 &#40;4&#44;0&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">25 &#40;2&#44;5&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
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                  \t\t\t\t">35 &#40;9&#44;2&#41;&nbsp;\t\t\t\t\t\t\n
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